Nuclear Medicine and Molecular Imaging
Last Update: 07/10/2024
Nuclear Medicine is the science in which the diagnosis and treatment of diseases are made using radioactive components. At Kolan Hospital Group Nuclear Medicine Department, organ functions are examined with nuclear medicine imaging methods.
Nuclear Medicine and Molecular Department includes positron emission tomography / computed tomography (PET-CT), gamma camera section where all nuclear medicine examinations can be performed, effort-pharmacological stress test and bone density measurement sections. Technical equipment consists of Siemens Biograph mCT, Siemens gamma cameras supported by E-soft computer systems, computerized stress test device, Lunar DPX bone densitometry and nuclear medicine laboratory auxiliary equipment.
Tests Applied in Our Nuclear Medicine Department;
Infection Imaging
- Labeled leukocyte scintigraphy
TUMOR IMAGING
- F-18 FDG oncological PET / CT
- F-18 NAF whole body bone scan PET / CT
- I-131 whole body scan scintigraphy
CARDIOLOGY
- Stress myocardial perfusion SPECT (with Tc-99m complexes)
- Pharmacological stress myocardial perfusion SPECT (Tc-99m complexes)
SKELETON SYSTEM
- Whole-body bone scintigraphy
- Three-phase bone scintigraphy
GENITOURINARY SYSTEM
- Dynamic kidney scintigraphy with diuretics (Tc-99m MAG3, Tc-99m DTPA Renal cortical (parenchyma) scintigraphy (static kidney scintigraphy, Tc-99m DMSA)
- Kidney scintigraphy with captopril (MAG3-DTPA)
- Indirect cystosyntigraphy
- Direct cystosyntigraphy
- Testicular scintigraphy
DIGESTIVE SYSTEM
- Gastroesophageal reflux scintigraphy
- Ectopic gastric mucosa (Meckel diverticulum) research
- Gastrointestinal bleeding study (Tc-99m RBC)
- Stomach Ejaculation Study (with Tc-99m complexes)
- Liver blood pool SPECT (Tc99m RBC)
- Salivary gland scintigraphy
THE RESPIRATORY SYSTEM
- Lung perfusion scintigraphy
- Quantitative lung perfusion scintigraphy
PLANT NERVOUS SYSTEM
- Brain perfusion SPECT
- F-18 FDG brain PET / CT
HEMATOLOGY
- lymphocintigraphy
- Selective spleen scintigraphy (Tc-99m labeled denatured erythrocyte)
ENDOCRINE SYSTEM
- Hyperthyroidism treatment
OTHER REVIEWS
- The Dakriosintigraf
- Bone density measurement
Radioactive Iodine Treatment
Radioactive iodine treatment, also known as “atomic therapy”, is an effective and reliable treatment method, which has been used all over the world for more than 60 years. ensures that the fast-running cells are devastated.
Rules to be followed in preparation before Radioactive Iodine treatment:
- 4-6 hours of fasting is required before application. However, you can drink water.
- Failure to use some medicines containing iodine or that may affect thyroid metabolism in the following periods before treatment will increase your treatment efficiency.
- Drugs used in the treatment of goiter (propycil, tyramosol) (3-5 days)
- Amiodarone (12-24 weeks)
Radioactive iodine is administered to the patient by the Nuclear Medicine doctor in capsule or liquid form in a glass of water.
Eating can be eaten two hours after taking the medicine. In order to prevent salivary glands from being affected by radioactive iodine, after the first 24 hours, one or two days, lemon, sugar should be absorbed, chewing gum, plenty of water, juice, etc. It should be consumed. Urine should be done frequently and plenty of water should be poured into the toilet. After the toilet, hands should be washed with plenty of water, showers should be taken every day, after every shower including underwear, socks, and head cover, all clothes should be changed and their clean should be worn.
Radioactive iodine; It is excreted from the body mostly with urine and to a lesser extent with saliva, sweat and feces. A significant part of the iodine taken by mouth is held by the thyroid gland. The amount of iodine trapped in other parts of the body is low and no damage to tissues has been reported.
Marked Leukocyte Scintigraphy
In our department, can be done in the few centers in Turkey are routinely labeled leukocyte scintigraphy by our experienced team. With this examination, it is possible to detect foci of infection in the cases of unknown fever and to detect prosthesis, bone and soft tissue infections.
Kidney Scintigraphy
- Dynamic Kidney Scintigraphy
- Static Kidney Scintigraphy
Dynamic Kidney Scintigraphy: DTPA is done using MAG3 or EC. With this examination, blood flow of the kidneys, filter function and working percentages (relative-split kidney functions) are determined. Static Kidney Scintigraphy: It is a method applied in patients with frequent urinary tract infection, pyelonephritis, reflux (urine leakage from the bladder to the kidneys) or kidney abnormality. With this examination, whether there is any loss in the functioning tissue of the kidneys, the working percentages of the kidneys relative to each other (relative-split kidney function) are determined.
Bone Scintigraphy
It is often used to assess orthopedic injuries, fractures, tumors, or unexplained pain. Bone scintigraphy evaluates whole body bones with a single injection. After the radioactive compound is injected into the vein, it passes into the soft tissue through the blood and is held by the skeletal system over time. Depending on the reason for this test, the moment of injection and the first 5 minutes of images are recorded in order to evaluate the blood flow and soft tissue stage in the area where the pain is present. Generally, 2-3 hours should be waited after the injection to make the bone tissue visible. After the waiting period is completed, the whole body is scanned. There is no need for a pre-examination preparation. However, as much liquid as possible (all kinds of drinks) should be drunk within the timeframe for injection imaging. This allows the radioactive compound to be excreted from soft tissue and to display the bones more clearly. The bladder should be emptied immediately before imaging.
Thyroid Scintigraphy (Tc-99m)
It gives information about the size, location, structure and function of the thyroid gland. Technetium pertechnetate (Tc-99m), a radioactive substance, is given into the vein, and the shoot is started after 15-20 minutes. Shooting takes about 15-20 minutes.
Myocardial Perfusion (Heart) Scintigraphy
It is a two-step test that takes images after resting and exertion to investigate the presence of obstruction in the coronary vessels feeding the left heart muscle. Effort is done with drugs that increase the heart rate (pharmacological) in the form of walking on the treadmill or in patients who can not exercise. In order to evaluate the blood flow in the resting state of the heart, the radioactive compound that has the ability to be held by the heart muscles is injected through the vascular access. After a waiting period of about 45-60 minutes, imaging is done and then effort test is done. When the target heart rate (varies depending on age) is reached in the treadmill exercise, the radioactive compound is injected through the vascular access. The second imaging is done 30 minutes after the exercise part of the test is completed. The shooting time is about 20 minutes. These two imaging findings are compared. Before the examination, the patient must be hungry. To the knowledge of the doctor, it may be necessary to discontinue or change the dose of any medication used.
PET / CT Imaging Technology
PET (Positron Emission Tomography) is a functional imaging method that provides physiological information required for clinical diagnosis based on changes in tissue metabolism. The most important advantage of PET is the use of positron emitting biological radioisotopes that mimic the natural components in the body. (Such as Carbon-11, Oxygen-15, Nitrogen-13, Flor-18)
For detailed information about PET CT, visit PET CT section.
For detailed information +90 444 1 443
Nuclear Medicine and Molecular Imaging Doctors

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